Somatostatin has many physiologic results: It inhibits secretion of numbers of endocrine, like gastrin, cholecystokinin, glucagon, growth hormone, insulin, secretin, pancreatic polypeptide, and vasoactive intestinal peptide. It reduces secretion of juice per bowel & pancreas. It reduces gi motility & inhibits contraction of the gallbladder. It inhibits a secretion of certain internal secretion from either a anterior pituitary.

A FDA has approved the usage of the salt form of this peptide, octreotide acetate, as an injectable depot formulation for the coarse of action of acromegaly, the coarse of action of diarrhea and flushing episodes associated with carcinoid syndrome, and professional assistance of diarrhoea inside patients by having vasoactive intestinal peptide-secreting tumors (VIPomas). Octreotide has likewise been utilized off-label for the professional assistance of severe, refractory diarrhoea from either more induces. These are utilized inside toxicology for the coarse of action of prolonged repeated hypoglycaemia fallowing sulfonylurea overdose.